Try and identify the type of spider that bit you. Clean the site of the spider bite well with soap and water. Apply a cool compress over the spider bite location. If the bite is on an extremity, elevate it. Aspirin or acetaminophen (Tylenol, others) and antihistamines may be used to relieve minor signs and symptoms in adults. Use caution when giving aspirin to children or teenagers.
If bitten by a brown recluse or black widow spider;
Cleanse the wound. Use soap and water to clean the wound and skin around the spider bite.
Slow the venom’s spread. If the spider bite is on an arm or a leg, tie a snug bandage above the bite and elevate the limb to help slow or halt the venom’s spread. Ensure that the bandage is not so tight that it cuts off circulation in your arm or leg.
Use a cold cloth at the spider bite location. Apply a cloth dampened with cold water or filled with ice.
Seek immediate medical attention. Treatment for the bite of a black widow may require an anti-venom medication. Doctors may treat a brown recluse spider bite with various medications.