Borussia Dortmund central defender Matt Hummels will be out of action until January due to an ankle injury.
Hummels and fellow defender Marcel Schmelzer, who were both injured for Germany in Tuesday’s 1-0 win over England at Wembley, will miss Saturday’s Bundesliga clash with Bayern Munich.
Hummels picked up a a heel injury in the friendly and has been ruled out for the rest of the year while Schmelzer suffered a calf muscle injury and will be sidelined for three weeks, Dortmund said on Wednesday.
Already hit by a string of injuries that have seen another key centre-back, Neven Subotic, out for the rest of the season with a knee injury, Coach Jurgen Klopp has been left searching for another central midfielder.
Dortmund host Bayern on Saturday at 17:30 GMT. The visitors are four points clear of their arch-rivals after 12 games.