Aaron Ramsey will be assessed within the next couple of days to determine the extent of the problem which forced him out of Wales 2-1 win in Andorra on Tuesday.
Wales coach Chris Coleman revealed after the match that the 23-year-old suffered an apparent ankle problem in the Uefa Euro 2016 qualifier.
The Arsenal midfielder limped off the pitch in the closing stages of the encounter, prompting fears he could sit out his club’s crucial game at home to Manchester City.
“He got kick on his ankle and twisted, it,” said Coleman.
“Coming to the end of the game, we’ve got players with experience so it was pointless taking the risk. I won’t do that with any of the players.
“Hopefully he’ll be okay for Arsenal at the weekend but we’ll have to see what the next 24-48 hours holds.”